120278-22-0

120278-22-0 structure

Name: salvinolone
Chemical Name: salvinolone
CAS Number: 120278-22-0
Molecular Formula: C₂₀H₂₆O₃
Molecular Weight: 314.41900
Catalog: Signaling Pathways Anti-infection Bacterial
Create Date: 2018-08-28 21:41:07
Modify Date: 2024-01-07 00:37:53
Salvinolone is active against methicillin-resistant Staphylococcus aureus (MRSA) and vancomycin-resistant Enterococcus (VRE). Salvinolone shows cytotoxic activity with an IC50 of 47.6 μM against the HL-60 tumor cell line for 72 h[1][2].

Name	salvinolone
Synonyms	5,6-Dihydroxy-7-isopropyl-1,1,4a-trimethyl-2,3,4,4a-tetrahydro-1H-phenanthren-9-one

Description	Salvinolone is active against methicillin-resistant Staphylococcus aureus (MRSA) and vancomycin-resistant Enterococcus (VRE). Salvinolone shows cytotoxic activity with an IC50 of 47.6 μM against the HL-60 tumor cell line for 72 h[1][2].
Related Catalog	Research Areas >> Cancer Research Areas >> Inflammation/Immunology Signaling Pathways >> Anti-infection >> Bacterial
References	[1]. Mingfeng Xu, et al. Bioactive diterpenes from Clerodendrum kaichianum. Nat Prod Commun. 2011 Jan;6(1):3-5. [2]. EnriqueAlvarez-Manzaneda, et al. First synthesis of picealactone C. A new route toward taxodione-related terpenoids from abietic acid. Tetrahedron Letters, Volume 48, Issue 6, 5 February 2007, Pages 989-992.