salvinolone

Modify Date: 2024-01-07 00:37:53

salvinolone Structure
salvinolone structure
Common Name salvinolone
CAS Number 120278-22-0 Molecular Weight 314.41900
Density 1.18±0.1 g/cm3 Boiling Point 498.8±45.0 °C at 760 mmHg
Molecular Formula C20H26O3 Melting Point 253-254 °C
MSDS N/A Flash Point N/A

 Use of salvinolone


Salvinolone is active against methicillin-resistant Staphylococcus aureus (MRSA) and vancomycin-resistant Enterococcus (VRE). Salvinolone shows cytotoxic activity with an IC50 of 47.6 μM against the HL-60 tumor cell line for 72 h[1][2].

 Names

Name salvinolone
Synonym More Synonyms

 salvinolone Biological Activity

Description Salvinolone is active against methicillin-resistant Staphylococcus aureus (MRSA) and vancomycin-resistant Enterococcus (VRE). Salvinolone shows cytotoxic activity with an IC50 of 47.6 μM against the HL-60 tumor cell line for 72 h[1][2].
Related Catalog
References

[1]. Mingfeng Xu, et al. Bioactive diterpenes from Clerodendrum kaichianum. Nat Prod Commun. 2011 Jan;6(1):3-5.  

[2]. EnriqueAlvarez-Manzaneda, et al. First synthesis of picealactone C. A new route toward taxodione-related terpenoids from abietic acid. Tetrahedron Letters, Volume 48, Issue 6, 5 February 2007, Pages 989-992.

 Chemical & Physical Properties

Density 1.18±0.1 g/cm3
Boiling Point 498.8±45.0 °C at 760 mmHg
Melting Point 253-254 °C
Molecular Formula C20H26O3
Molecular Weight 314.41900
Exact Mass 314.18800
PSA 57.53000
LogP 4.81170

 Synonyms

5,6-Dihydroxy-7-isopropyl-1,1,4a-trimethyl-2,3,4,4a-tetrahydro-1H-phenanthren-9-one