135295-27-1

135295-27-1 structure

Name: 9-(3-fluoro-2-phosphonylmethoxypropyl)adenine
Chemical Name: (1-(6-amino-9H-purin-9-yl)-3-fluoropropan-2-yloxy)methylphosphonic acid
CAS Number: 135295-27-1
Molecular Formula: C₉H₁₃FN₅O₄P
Molecular Weight: 305.20300
Catalog: Signaling Pathways Anti-infection HIV
Create Date: 2018-04-26 09:22:56
Modify Date: 2024-01-26 14:54:39
(2RS)-FPMPA can be used for synthesis of antiretroviral agents against HIV-1 and HIV-2[1].

Name	(1-(6-amino-9H-purin-9-yl)-3-fluoropropan-2-yloxy)methylphosphonic acid
Synonyms	9-(RS)-(3-fluoro-2-phosphonomethoxypropyl)adenine RS-FPMPA 9-(3-Fluoro-2-phosphonylmethoxypropyl)-adenine [2-(6-Amino-purin-9-yl)-1-fluoromethyl-ethoxymethyl]-phosphonic acid

Description	(2RS)-FPMPA can be used for synthesis of antiretroviral agents against HIV-1 and HIV-2[1].
Related Catalog	Signaling Pathways >> Anti-infection >> HIV Research Areas >> Infection
References	[1]. Balzarini J, et al. 9-[(2RS)-3-fluoro-2-phosphonylmethoxypropyl] derivatives of purines: a class of highly selective antiretroviral agents in vitro and in vivo. Proc Natl Acad Sci U S A. 1991 Jun 1;88(11):4961-5.