13497-24-0

13497-24-0 structure

Name: Bis-methacrylate-PEG5
Chemical Name: tetraethyleneglycol dimethacrylate
CAS Number: 13497-24-0
Molecular Formula: C₁₈H₃₀O₈
Molecular Weight: 374.42600
Catalog: Signaling Pathways PROTAC PROTAC Linker
Create Date: 2018-01-15 05:18:45
Modify Date: 2024-01-02 17:50:03
Bis-methacrylate-PEG5 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name	tetraethyleneglycol dimethacrylate
Synonyms	pentaethylene glycol dimethacrylate

Description	Bis-methacrylate-PEG5 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker
Target	PEGs
In Vitro	PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References	[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562