65597-47-9

65597-47-9 structure
65597-47-9 structure
  • Name: Catechin 7-O-beta-D-glucopyranoside
  • Chemical Name: (+)-catechin 7-O-β-D-xyloside
  • CAS Number: 65597-47-9
  • Molecular Formula: C10H9N3O2
  • Molecular Weight: 203.19700
  • Catalog: Research Areas Inflammation/Immunology
  • Create Date: 2017-05-04 12:49:10
  • Modify Date: 2024-01-08 12:16:27
  • Catechin 7-O-beta-D-glucopyranoside is an orally active natural product found in Ulmus davidiana and Paeonia obovata. Catechin 7-O-β-D-glucopyranoside shows antioxidant and anti-inflammatory activities, and attenuates mitochondrial dysfunction. Catechin 7-O-beta-D-glucopyranoside can be used in intestinal inflammatory disease research[1][2][3].

Name (+)-catechin 7-O-β-D-xyloside
Synonyms 5-oxo-1-phenyl-4H-pyrazole-3-carboxamide
(+)-catechin 7-O-beta-D-xyloside
5-oxo-1-phenyl-4,5-dihydro-1h-pyrazole-3-carboxamide
Description Catechin 7-O-beta-D-glucopyranoside is an orally active natural product found in Ulmus davidiana and Paeonia obovata. Catechin 7-O-β-D-glucopyranoside shows antioxidant and anti-inflammatory activities, and attenuates mitochondrial dysfunction. Catechin 7-O-beta-D-glucopyranoside can be used in intestinal inflammatory disease research[1][2][3].
Related Catalog
In Vitro Catechin 7-O-β-D-glucopyranoside (10 μg/mL; 24 h) shows protective effect against Streptozotocin-induced cell damage by its antioxidant effects and the attenuation of mitochondrial dysfunction[3]. Western Blot Analysis[3] Cell Line: RINm5F rat pancreatic β-cells Concentration: 10 μg/mL Incubation Time: 24 hours Result: Increased the MnSOD level attenuated by Streptozotocin treatment. Restored the Streptozotocin-induced reduction in mitochondrial CAT level.
In Vivo Catechin 7-O-β-D-glucopyranoside (intraperitoneal injection; 10 mg/kg; once) treatment shows mild protective effect against lethality induced by LPS/D-GalN[1]. Catechin 7-O-β-D-glucopyranoside (oral administration; 10 mg/kg; once daily; 7 d) treatment prevents intestinal inflammatory damages in TNBS model of rat colitis[2]. Animal Model: Mice injected with LPS/D-GalN[1] Dosage: 10 mg/kg Administration: Intraperitoneal injection; 10 mg/kg; once Result: Showed 80% LPS/DGalN-induced lethality in mice. Animal Model: Rat model of trinitrobenzenesulfonic acid (TNBS)-induced colitis [2] Dosage: 10 mg/kg Administration: Oral administration; 10 mg/kg; once daily; 7 days Result: Suppressed body weight loss and intestinal inflammatory damages in TNBS-induced colitic rats. Reduced myeloperoxidase activity and malondialdehyde level, but increased glutathione level in the TNBS colitic rats.
Molecular Formula C10H9N3O2
Molecular Weight 203.19700
Exact Mass 203.06900
PSA 75.76000
LogP 0.46550