76015-42-4

76015-42-4 structure

Name: 6-Methoxytricin
Chemical Name: 5,7,4'-trihydroxy-6,3',5'-trimethoxyflavone
CAS Number: 76015-42-4
Molecular Formula: C₁₈H₁₆O₈
Molecular Weight: 360.31500
Catalog: Signaling Pathways Metabolic Enzyme/Protease Aldose Reductase
Create Date: 2018-06-21 15:57:11
Modify Date: 2024-01-03 08:51:31
6-Methoxytricin (Compound 6) is an flavonoid isolated from Artemisia iwayomogi. 6-Methoxytricin (Compound 6) is an inhibitor on aldose reductase (AR) and advanced glycation endproduct (AGE) formation activities with IC50 values of 30.29 μM and 134.88 μM, respectively. 6-Methoxytricin (Compound 6) has potential as an anti-diabetic complications agent[1].

Name	5,7,4'-trihydroxy-6,3',5'-trimethoxyflavone
Synonyms	5,7-Dihydroxy-2-(4-hydroxy-3,5-dimethoxy-phenyl)-6-methoxy-chromen-4-one 6-methoxytricin 6,3',5'-trimethoxyapigenin

Description	6-Methoxytricin (Compound 6) is an flavonoid isolated from Artemisia iwayomogi. 6-Methoxytricin (Compound 6) is an inhibitor on aldose reductase (AR) and advanced glycation endproduct (AGE) formation activities with IC50 values of 30.29 μM and 134.88 μM, respectively. 6-Methoxytricin (Compound 6) has potential as an anti-diabetic complications agent[1].
Related Catalog	Signaling Pathways >> Metabolic Enzyme/Protease >> Aldose Reductase Research Areas >> Metabolic Disease
Target	IC50: 30.29 μM (AR); 134.88 μM (AGE) (6-Methoxytricin)[1]
References	[1]. Lee YK, et al. Inhibitory Effect of Chemical Constituents Isolated from Artemisia iwayomogi on Polyol Pathway and Simultaneous Quantification of Major Bioactive Compounds. Biomed Res Int. 2017;2017:7375615.