152290-47-6

152290-47-6 structure

Name: 5',5-Difluoro BAPTA tetrapotassium
Chemical Name: N,N'-[1,2-Ethanediylbis[oxy(4-fluoro-2,1-phenylene)]]bis[N-(carboxymethyl)glycine] tetrapotassium salt
CAS Number: 152290-47-6
Molecular Formula: C₂₂H₁₈F₂N₂O_10.4K
Molecular Weight: 664.7757264
Catalog: Research Areas Others
Create Date: 2018-11-30 21:30:22
Modify Date: 2024-07-13 08:44:01
5,5'-Difluoro BAPTA tetrapotassium is a difluoro-derivative of BAPTA (HY-100168). 5,5'-Difluoro BAPTA tetrapotassium shows large 19F NMR chemical shifts upon chelating divalent cations. 5,5'-Difluoro BAPTA tetrapotassium has high selectivity for Ca2+. 5,5'-Difluoro BAPTA tetrapotassium can inhibit the growth of pollen tube[1][2].

Name	N,N'-[1,2-Ethanediylbis[oxy(4-fluoro-2,1-phenylene)]]bis[N-(carboxymethyl)glycine] tetrapotassium salt

Description	5,5'-Difluoro BAPTA tetrapotassium is a difluoro-derivative of BAPTA (HY-100168). 5,5'-Difluoro BAPTA tetrapotassium shows large 19F NMR chemical shifts upon chelating divalent cations. 5,5'-Difluoro BAPTA tetrapotassium has high selectivity for Ca2+. 5,5'-Difluoro BAPTA tetrapotassium can inhibit the growth of pollen tube[1][2].
Related Catalog	Research Areas >> Others Signaling Pathways >> Others >> Others
In Vitro	Fe2+ ion concentrations were measured following addition of 5 mM 5,5'-Difluoro BAPTA tetrapotassium to the culture medium. Fe2+ forms a complex with 5,5'-Difluoro BAPTA tetrapotassium (Kd=50 nM) that exhibits a characteristic peak down-field from biological ions such as Ca2+ and Zn2+[3].
References	[1]. Bar-Shir A, et al. Metal ion sensing using ion chemical exchange saturation transfer 19F magnetic resonance imaging. J Am Chem Soc. 2013 Aug 21;135(33):12164-7. [2]. Pierson ES, et al. Pollen tube growth is coupled to the extracellular calcium ion flux and the intracellular calcium gradient: effect of BAPTA-type buffers and hypertonic media. Plant Cell. 1994 Dec;6(12):1815-28. [3]. Kostellow AB, et al. Iron-catalyzed lipid peroxidation in aortic cells in vitro: protective effect of extracellular magnesium. Atherosclerosis. 2004 Jul;175(1):15-22.

Molecular Formula	C₂₂H₁₈F₂N₂O_10.4K
Molecular Weight	664.7757264