88894-91-1

88894-91-1 structure

Name: GRF (1-44) (BOVINE)
Chemical Name: GRE(1-44),Bovine
CAS Number: 88894-91-1
Molecular Formula: C₂₂₀H₃₆₆N₇₂O₆₆S
Molecular Weight: 5107.84
Catalog: Signaling Pathways GPCR/G Protein GHSR
Create Date: 2018-12-31 18:53:44
Modify Date: 2024-01-02 10:23:28
GHRF, bovine (bGRF(1-44)-NH2) is the bovine growth hormone (GH)-releasing factor (GHRF). GHRF, bovine increases the release of bovine GH, and shows a synergistic effect with Hydrocortisone (HY-N0583)[1][2].

Name	GRE(1-44),Bovine
Synonyms	MFCD00081670 GHRF, bovine

Description	GHRF, bovine (bGRF(1-44)-NH2) is the bovine growth hormone (GH)-releasing factor (GHRF). GHRF, bovine increases the release of bovine GH, and shows a synergistic effect with Hydrocortisone (HY-N0583)[1][2].
Related Catalog	Research Areas >> Endocrinology Signaling Pathways >> GPCR/G Protein >> GHSR
In Vitro	GHRF, bovine (0.001 nM-100 nM; 6 h) increases growth hormone (GH) release from bovine anterior pituitary cells, with maximum release of 262% above control at 100 nM[1]. GHRF, bovine (0.0001 nM-100 nM; 24 h) linearly increases GH secretion and is enhanced by Hydrocortisone (HY-N0583) (Cortisol, 10 ng/mL) in anterior pituitary cells cultured in media containing fetal calf serum (FCS)[1].
In Vivo	GHRF, bovine (12 mg/d; i.v.drip; from 118 to 181 d postpartum) has no influence on the mRNA abundance of the liver-type glucose transporter in the liver or kidney of postpartum bovine[2]. GHRF, bovine (12 mg/d; i.v.drip; from 118 to 181 d postpartum) also doesn’t alter the mRNA abundance of the erythrocyte-type or the intestinal-type glucose transporter in the kidney of postpartum bovine, but results individual differences in the mRNA abundance of the intestinal-type glucose transporter in liver[2].

Hazard Codes	Xn
WGK Germany	3.0