1257213-50-5

1257213-50-5 structure

Name: BMS-986020
Chemical Name: BMS-986020
CAS Number: 1257213-50-5
Molecular Formula: C₂₉H₂₆N₂O₅
Molecular Weight: 482.527
Catalog: Signaling Pathways GPCR/G Protein LPL Receptor
Create Date: 2018-06-26 03:19:39
Modify Date: 2024-01-06 20:52:35
BMS-986020 is an LPA1 antagonist.target: LPA1BMS-986020 is in Phase 2 clinical development for treating idiopathic pulmonary fibrosis. BMS-986020 selectively inhibits the LPA receptor, which is involved in binding of the signaling molecule lysophosphatidic acid, which in turn is involved in a host of diverse biological functions, such as cell proliferation, platelet aggregation, smooth muscle contraction and others.

Name	BMS-986020
Synonyms	1-{4'-[3-Methyl-4-({[(1R)-1-phenylethoxy]carbonyl}amino)-1,2-oxazol-5-yl]-4-biphenylyl}cyclopropanecarboxylic acid Cyclopropanecarboxylic acid, 1-[4'-[3-methyl-4-[[[(1R)-1-phenylethoxy]carbonyl]amino]-5-isoxazolyl][1,1'-biphenyl]-4-yl]-

Description	BMS-986020 is an LPA1 antagonist.target: LPA1BMS-986020 is in Phase 2 clinical development for treating idiopathic pulmonary fibrosis. BMS-986020 selectively inhibits the LPA receptor, which is involved in binding of the signaling molecule lysophosphatidic acid, which in turn is involved in a host of diverse biological functions, such as cell proliferation, platelet aggregation, smooth muscle contraction and others.
Related Catalog	Signaling Pathways >> GPCR/G Protein >> LPL Receptor Research Areas >> Cancer
References	[1]. Kihara Y et al. Lysophospholipid receptors in drug discovery. Exp Cell Res. 2015 May 1;333(2):171-7.