Name | SU 5214 |
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Synonyms |
2H-Indol-2-one, 1,3-dihydro-3-[(2-methoxyphenyl)methylene]-, (3Z)-
3-(2-methoxybenzylidene)indolin-2-one (3Z)-3-(2-Methoxybenzylidene)-1,3-dihydro-2H-indol-2-one |
Description | SU5214 is a potent VEGFR2 inhibitor extracted from patent US5834504A, SU5214, has the IC50s of 14.8 µM (FLK-1) and 36.7 µM (EGFR), respectively[1]. |
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Related Catalog | |
Target |
Flk-1:14.8 μM (IC50) |
References |
[1]. Tang et al. 3-(2'-halobenzylidenyl)-2-indolinone compounds for the treatment of disease. US5834504A. |
Density | 1.2±0.1 g/cm3 |
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Boiling Point | 469.4±45.0 °C at 760 mmHg |
Molecular Formula | C16H13NO2 |
Molecular Weight | 251.280 |
Flash Point | 237.7±28.7 °C |
Exact Mass | 251.094635 |
LogP | 3.42 |
Vapour Pressure | 0.0±1.2 mmHg at 25°C |
Index of Refraction | 1.657 |
Storage condition | -20℃ |