SU5214

Modify Date: 2024-01-22 17:08:31

SU5214 Structure
SU5214 structure
Common Name SU5214
CAS Number 186611-04-1 Molecular Weight 251.280
Density 1.2±0.1 g/cm3 Boiling Point 469.4±45.0 °C at 760 mmHg
Molecular Formula C16H13NO2 Melting Point N/A
MSDS N/A Flash Point 237.7±28.7 °C

 Use of SU5214


SU5214 is a potent VEGFR2 inhibitor extracted from patent US5834504A, SU5214, has the IC50s of 14.8 µM (FLK-1) and 36.7 µM (EGFR), respectively[1].

 Names

Name SU 5214
Synonym More Synonyms

 SU5214 Biological Activity

Description SU5214 is a potent VEGFR2 inhibitor extracted from patent US5834504A, SU5214, has the IC50s of 14.8 µM (FLK-1) and 36.7 µM (EGFR), respectively[1].
Related Catalog
Target

Flk-1:14.8 μM (IC50)

References

[1]. Tang et al. 3-(2'-halobenzylidenyl)-2-indolinone compounds for the treatment of disease. US5834504A.

 Chemical & Physical Properties

Density 1.2±0.1 g/cm3
Boiling Point 469.4±45.0 °C at 760 mmHg
Molecular Formula C16H13NO2
Molecular Weight 251.280
Flash Point 237.7±28.7 °C
Exact Mass 251.094635
LogP 3.42
Vapour Pressure 0.0±1.2 mmHg at 25°C
Index of Refraction 1.657
Storage condition -20℃

 Synonyms

2H-Indol-2-one, 1,3-dihydro-3-[(2-methoxyphenyl)methylene]-, (3Z)-
3-(2-methoxybenzylidene)indolin-2-one
(3Z)-3-(2-Methoxybenzylidene)-1,3-dihydro-2H-indol-2-one
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