202592-23-2
202592-23-2 structure
- Name: JQ-1 carboxylic acid
- Chemical Name: (+)-JQ1 carboxylic acid
- CAS Number: 202592-23-2
- Molecular Formula: C19H17ClN4O2S
- Molecular Weight: 400.882
- Catalog: Signaling Pathways Epigenetics Epigenetic Reader Domain
- Create Date: 2018-05-20 08:00:00
- Modify Date: 2024-01-02 09:41:00
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JQ-1 carboxylic acid is a highly potent, selective and cell-permeable BRD4 inhibitor with IC50s of 77 nM and 33 nM for BRD4(1) and BRD4(2), respectively.
| Name | (+)-JQ1 carboxylic acid |
|---|---|
| Synonyms |
6H-Thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepine-6-acetic acid, 4-(4-chlorophenyl)-2,3,9-trimethyl-, (6S)-
[(6S)-4-(4-Chlorophenyl)-2,3,9-trimethyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepin-6-yl]acetic acid JQ-1 (carboxylic acid) |
| Description | JQ-1 carboxylic acid is a highly potent, selective and cell-permeable BRD4 inhibitor with IC50s of 77 nM and 33 nM for BRD4(1) and BRD4(2), respectively. |
|---|---|
| Related Catalog | |
| References |
| Density | 1.5±0.1 g/cm3 |
|---|---|
| Boiling Point | 661.6±65.0 °C at 760 mmHg |
| Molecular Formula | C19H17ClN4O2S |
| Molecular Weight | 400.882 |
| Flash Point | 353.9±34.3 °C |
| Exact Mass | 400.076080 |
| LogP | 2.79 |
| Vapour Pressure | 0.0±2.1 mmHg at 25°C |
| Index of Refraction | 1.737 |
| Storage condition | 2-8℃ |