19536-25-5

19536-25-5 structure
19536-25-5 structure
  • Name: 2-O-Acetyl-20-hydroxyecdysone
  • Chemical Name: 20-hydroxyecdysone, 2-acetate
  • CAS Number: 19536-25-5
  • Molecular Formula: C29H46O8
  • Molecular Weight: 522.67
  • Catalog: Research Areas Neurological Disease
  • Create Date: 2018-05-20 08:00:00
  • Modify Date: 2024-01-10 08:44:11
  • 2-O-Acetyl-20-hydroxyecdysone, an ecdysterones in insects and terrestrial plants, inhibits amyloid-β42 (Aβ42)-induced cytotoxicity. 2-O-Acetyl-20-hydroxyecdysone could decrease Aβ oligomer formation through promotion of fibrogenesis, transforming Aβ oligomers to the low-toxicity fibrils[1].

Name 20-hydroxyecdysone, 2-acetate
Synonyms β-Ecdysone 2-acetate
2-O-Acetyl-20-hydroxyecdysone
Description 2-O-Acetyl-20-hydroxyecdysone, an ecdysterones in insects and terrestrial plants, inhibits amyloid-β42 (Aβ42)-induced cytotoxicity. 2-O-Acetyl-20-hydroxyecdysone could decrease Aβ oligomer formation through promotion of fibrogenesis, transforming Aβ oligomers to the low-toxicity fibrils[1].
Related Catalog
References

[1]. Yang SG, et al. Diverse ecdysterones show different effects on amyloid-β42 aggregation but all uniformly inhibit amyloid-β42-induced cytotoxicity. J Alzheimers Dis. 2010;22(1):107-17.

Density 1.26±0.1 g/cm3
Boiling Point 707.3±60.0 °C
Melting Point 218-220 ºC
Molecular Formula C29H46O8
Molecular Weight 522.67
Exact Mass 522.319
PSA 144.52
LogP 2.4248
Water Solubility Very slightly soluble (0.24 g/L) (25 ºC)
Hazard Codes Xi