329319-20-2

329319-20-2 structure

Name: Sanggenol L
Chemical Name: Sanggenol L
CAS Number: 329319-20-2
Molecular Formula: C₂₅H₂₆O₆
Molecular Weight: 422.47
Catalog: Signaling Pathways Apoptosis MDM-2/p53
Create Date: 2018-05-22 08:00:00
Modify Date: 2024-01-12 09:56:41
Sanggenol L induces caspase-dependent and caspase-independent apoptosis in melanoma skin cancer cells[1]. Sanggenol L induces of apoptosis via suppression of PI3K/Akt/mTOR signaling and cell cycle arrest via activation of p53 in p

Name	Sanggenol L
Synonyms	4H,8H-Benzo[1,2-b:3,4-b']dipyran-4-one, 2-(2,4-dihydroxyphenyl)-2,3,9,10-tetrahydro-5-hydroxy-8-methyl-8-(4-methyl-3-penten-1-yl)- 2-(2,4-Dihydroxyphenyl)-5-hydroxy-8-methyl-8-(4-methyl-3-penten-1-yl)-2,3,9,10-tetrahydro-4H,8H-pyrano[2,3-f]chromen-4-one

Description	Sanggenol L induces caspase-dependent and caspase-independent apoptosis in melanoma skin cancer cells[1]. Sanggenol L induces of apoptosis via suppression of PI3K/Akt/mTOR signaling and cell cycle arrest via activation of p53 in p
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Apoptosis >> MDM-2/p53
References	[1]. Won YS, Seo KI. Sanggenol L promotes apoptotic cell death in melanoma skin cancer cells through activation of caspase cascades and apoptosis-inducing factor. Food Chem Toxicol. 2020;138:111221. [2]. Won YS, Seo KI. Sanggenol L Induces Apoptosis and Cell Cycle Arrest via Activation of p53 and Suppression of PI3K/Akt/mTOR Signaling in Human Prostate Cancer Cells. Nutrients. 2020;12(2):488. Published 2020 Feb 14.