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37951-13-6

37951-13-6 structure
37951-13-6 structure
  • Name: Flavokawain A
  • Chemical Name: Flavokawain A
  • CAS Number: 37951-13-6
  • Molecular Formula: C18H18O5
  • Molecular Weight: 314.332
  • Catalog: Signaling Pathways Apoptosis Apoptosis
  • Create Date: 2018-01-31 23:11:29
  • Modify Date: 2024-01-10 16:15:29
  • Flavokawain A, a chalcone extracted from Kava, has anticarcinogenic effect. Flavokawain A induces apoptosis in bladder cancer cells by involvement of bax protein-dependent and mitochondria-dependent apoptotic pathway and suppresses tumor growth in mice[1].

Name Flavokawain A
Synonyms (2E)-1-(2-Hydroxy-4,6-dimethoxyphenyl)-3-(4-methoxyphenyl)prop-2-en-1-one
(2E)-1-(2-Hydroxy-4,6-dimethoxyphenyl)-3-(4-methoxyphenyl)-2-propen-1-one
1OR CQ EO1 BV1U1R DO1 &&E Form
2-Propen-1-one, 1-(2-hydroxy-4,6-dimethoxyphenyl)-3-(4-methoxyphenyl)-, (2E)-
MFCD00017174
(E)-1-(2-Hydroxy-4,6-dimethoxyphenyl)-3-(4-methoxyphenyl)prop-2-en-1-one
2′-Hydroxy-4,4′,6′-trimethoxychalcone
Description Flavokawain A, a chalcone extracted from Kava, has anticarcinogenic effect. Flavokawain A induces apoptosis in bladder cancer cells by involvement of bax protein-dependent and mitochondria-dependent apoptotic pathway and suppresses tumor growth in mice[1].
Related Catalog
References

[1]. Zi X, et al. Flavokawain A, a novel chalcone from kava extract, induces apoptosis in bladder cancer cells by involvement of Bax protein-dependent and mitochondria-dependent apoptotic pathway and suppresses tumor growth in mice. Cancer Res. 2005 Apr 15;65(8):3479-86.

Density 1.2±0.1 g/cm3
Boiling Point 529.9±50.0 °C at 760 mmHg
Melting Point 114℃
Molecular Formula C18H18O5
Molecular Weight 314.332
Flash Point 193.2±23.6 °C
Exact Mass 314.115417
LogP 3.96
Vapour Pressure 0.0±1.4 mmHg at 25°C
Index of Refraction 1.600