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1159588-21-2

1159588-21-2 structure
1159588-21-2 structure
  • Name: (Z)-Pitavastatin calcium
  • Chemical Name: (Z)-Pitavastatin Calcium Salt
  • CAS Number: 1159588-21-2
  • Molecular Formula: C25H24FNO4.1/2Ca
  • Molecular Weight: 420.4528232
  • Catalog: Research Areas Others
  • Create Date: 2018-12-18 18:13:49
  • Modify Date: 2024-01-03 15:26:59
  • (Z)-Pitavastatin calcium is the Z-Isomer of Pitavastatin hemicacium. Pitavastatin calcium is a potent hydroxymethylglutaryl-CoA (HMG-CoA) reductase inhibitor. Pitavastatin calcium inhibits cholesterol synthesis from acetic acid with an IC50 of 5.8 nM in HepG2 cells[1].

Name (Z)-Pitavastatin Calcium Salt
Synonyms Pitavastatin Impurity 5
Description (Z)-Pitavastatin calcium is the Z-Isomer of Pitavastatin hemicacium. Pitavastatin calcium is a potent hydroxymethylglutaryl-CoA (HMG-CoA) reductase inhibitor. Pitavastatin calcium inhibits cholesterol synthesis from acetic acid with an IC50 of 5.8 nM in HepG2 cells[1].
Related Catalog
References

[1]. Kajinami K, et al. Pitavastatin: efficacy and safety profiles of a novel synthetic HMG-CoA reductase inhibitor.Cardiovasc Drug Rev. 2003 Fall;21(3):199-215.

Molecular Formula C25H24FNO4.1/2Ca
Molecular Weight 420.4528232