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  • DC Chemicals Limited
  • China
  • Product Name: IDO-IN-8
  • Price: $Inquiry/100mg $Inquiry/250mg $Inquiry/1g
  • Purity: 98.0%
  • Stocking Period: 3 Day
  • Contact: Tony Cao

1402837-77-7

1402837-77-7 structure
1402837-77-7 structure
  • Name: IDO-IN-8
  • Chemical Name: IDO-IN-8
  • CAS Number: 1402837-77-7
  • Molecular Formula: C18H21FN2O2
  • Molecular Weight: 316.370
  • Catalog: Signaling Pathways Metabolic Enzyme/Protease Indoleamine 2,3-Dioxygenase (IDO)
  • Create Date: 2018-01-11 13:47:48
  • Modify Date: 2024-01-24 19:53:50
  • IDO-IN-8 (NLG-1487) is an indoleamine 2,3-dioxygenase (IDO) inhibitor extracted from patent WO WO2012142237A1, compound 1487, has an IC50 of 1-10 μM.

Name IDO-IN-8
Synonyms 5H-Imidazo[5,1-a]isoindole-5-ethanol, 6-fluoro-α-(trans-4-hydroxycyclohexyl)-, (αS,5R)-
trans-4-{(1S)-2-[(5R)-6-Fluoro-5H-imidazo[5,1-a]isoindol-5-yl]-1-hydroxyethyl}cyclohexanol
Description IDO-IN-8 (NLG-1487) is an indoleamine 2,3-dioxygenase (IDO) inhibitor extracted from patent WO WO2012142237A1, compound 1487, has an IC50 of 1-10 μM.
Related Catalog
Target

IDO:1-10 μM (IC50)

In Vitro IDO-IN-8 (Compound 1487) is an indoleamine 2,3-dioxygenase (IDO) inhibitor with an IC50 of 1-10 μM (this is the concentration of IDO-IN-8 at which inhibits 50% of enzymatic activity using recombinant human IDO)[1].
References

[1]. Mautino, et al. Preparation of fused imidazole derivatives as IDO inhibitors. From PCT Int. Appl. (2012), 20121018.

Density 1.4±0.1 g/cm3
Boiling Point 555.4±35.0 °C at 760 mmHg
Molecular Formula C18H21FN2O2
Molecular Weight 316.370
Flash Point 289.7±25.9 °C
Exact Mass 316.158691
LogP 1.28
Vapour Pressure 0.0±1.6 mmHg at 25°C
Index of Refraction 1.683
Storage condition 2-8℃