1802706-04-2
1802706-04-2 structure
- Name: RORγ-IN-1
- Chemical Name: RORγ-IN-1
- CAS Number: 1802706-04-2
- Molecular Formula: C27H35F3N4O3S
- Molecular Weight: 552.652
- Catalog: Signaling Pathways Metabolic Enzyme/Protease ROR
- Create Date: 2018-06-18 03:12:11
- Modify Date: 2024-01-13 19:35:01
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RORγ-IN-1 is a RORγ inhibitor extracted from patent US 9481674 B1, has a Ki of <100 nM.
| Name | RORγ-IN-1 |
|---|---|
| Synonyms |
5H-Pyrrolo[3,4-b]pyridine-3-carboxamide, N-[[5-(ethylsulfonyl)-2-pyridinyl]methyl]-6,7-dihydro-7-(1-methylethyl)-6-[[trans-4-(trifluoromethyl)cyclohexyl]methyl]-, (7S)-
(7S)-N-{[5-(Ethylsulfonyl)-2-pyridinyl]methyl}-7-isopropyl-6-{[trans-4-(trifluoromethyl)cyclohexyl]methyl}-6,7-dihydro-5H-pyrrolo[3,4-b]pyridine-3-carboxamide |
| Description | RORγ-IN-1 is a RORγ inhibitor extracted from patent US 9481674 B1, has a Ki of <100 nM. |
|---|---|
| Related Catalog | |
| Target |
Ki: <100 nM (RORγ)[1] |
| References |
[1]. David A. Claremon, et al. Dihydropyrrolopyridine inhibitors of ROR-gamma . US 9481674 B1. |
| Density | 1.3±0.1 g/cm3 |
|---|---|
| Boiling Point | 659.4±55.0 °C at 760 mmHg |
| Molecular Formula | C27H35F3N4O3S |
| Molecular Weight | 552.652 |
| Flash Point | 352.6±31.5 °C |
| Exact Mass | 552.238220 |
| LogP | 2.54 |
| Vapour Pressure | 0.0±2.0 mmHg at 25°C |
| Index of Refraction | 1.541 |