211516-63-1

211516-63-1 structure

Name: Oleanolic acid derivative 2
Chemical Name: Oleanolic acid derivative 2
CAS Number: 211516-63-1
Molecular Formula: C₂₈H₄₂O₃
Molecular Weight: 426.631
Catalog: Research Areas Inflammation/Immunology
Create Date: 2018-02-26 01:39:43
Modify Date: 2024-01-19 14:07:05
Oleanolic acid derivative 2 is an oleanolic acid derivative, which is a novel triterpenoid-steroid hybrid molecule.

Name	Oleanolic acid derivative 2
Synonyms	7aH-Cyclopenta[a]chrysene-7a-carboxylic acid, 1,2,3,3a,4,5,5a,5b,6,7,8,9,10,11,11a,13,13a,13b-octadecahydro-5a,5b,10,10,13b-pentamethyl-3-oxo-, methyl ester, (3aR,5aR,5bS,7aS,11aS,13aR,13bR)- Methyl (3aR,5aR,5bS,7aS,11aS,13aR,13bR)-5a,5b,10,10,13b-pentamethyl-3-oxo-1,2,3,3a,4,5,5a,5b,6,7,8,9,10,11,11a,13,13a,13b-octadecahydro-7aH-cyclopenta[a]chrysene-7a-carboxylate

Description	Oleanolic acid derivative 2 is an oleanolic acid derivative, which is a novel triterpenoid-steroid hybrid molecule.
Related Catalog	Signaling Pathways >> Others >> Others Research Areas >> Inflammation/Immunology
In Vitro	Oleanolic acid suppress transcription or translation of inducible nitric oxide synthase (iNOS) and inducible cyclooxygenase (COX-2) genes. HY-18003 is extracted from the reference, compound 12a. For the transformation of olefin 9a (HY-18002) into ketone 12a (HY-18003), the obvious ozonolysis cannot be used because ozone also reacts with the C-12 olefin of oleanane triterpenoids to give the 12R,13R-epoxide, 12-ketone,9 and 12R-hydroxy lactone.[1].
References	[1]. Tadashi Honda, et al. Design and Synthesis of 23,24-Dinoroleanolic Acid Derivatives, Novel Triterpenoid-Steroid Hybrid Molecules. J. Org. Chem., 1998, 63 (14), pp 4846-4849.