896106-16-4
896106-16-4 structure
- Name: Imiquimod maleate
- Chemical Name: Imiquimod maleate
- CAS Number: 896106-16-4
- Molecular Formula: C18H20N4O4
- Molecular Weight: 356.376
- Catalog: Signaling Pathways Autophagy Autophagy
- Create Date: 2018-04-28 23:05:20
- Modify Date: 2024-01-11 16:11:02
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Imiquimod maleate is an immune response modifier that acts as a toll-like receptor 7agonist.
| Name | Imiquimod maleate |
|---|---|
| Synonyms |
1H-Imidazo[4,5-c]quinolin-4-amine, 1-(2-methylpropyl)-, (2Z)-2-butenedioate (1:1)
1-Isobutyl-1H-imidazo[4,5-c]quinolin-4-amine (2Z)-2-butenedioate (1:1) |
| Description | Imiquimod maleate is an immune response modifier that acts as a toll-like receptor 7agonist. |
|---|---|
| Related Catalog | |
| Target |
Toll-like receptor 7 |
| In Vivo | In animal models, imiquimod stimulates the innate immune response by increasing NK cell activity, activating macrophages to secretecytokines and nitric oxide, and inducing proliferation and differentiation of B lymphocytes. Imiquimod stimulates the innate immune response through induction, synthesis, and release of cytokines, including interferon-a (IFN-α), interleukin (IL)-6, and tumour necrosis factor (TNF)-α[1]. |
| References |
[1]. Bilu D, et al. Imiquimod: modes of action. Br J Dermatol. 2003 Nov;149 Suppl 66:5-8. |
| Molecular Formula | C18H20N4O4 |
|---|---|
| Molecular Weight | 356.376 |
| Exact Mass | 356.148468 |
| Storage condition | 2-8℃ |