287399-47-7

287399-47-7 structure
287399-47-7 structure
  • Name: AU-224
  • Chemical Name: AU-224
  • CAS Number: 287399-47-7
  • Molecular Formula: C19H28ClN3O4
  • Molecular Weight: 397.9
  • Catalog: Research Areas Metabolic Disease
  • Create Date: 2018-01-23 13:03:23
  • Modify Date: 2024-01-11 09:21:09
  • AU-224 is a benzamide derivative used as a promising gastrointestinal prokinetic agent without significant side effects.

Name AU-224
Description AU-224 is a benzamide derivative used as a promising gastrointestinal prokinetic agent without significant side effects.
Related Catalog
In Vitro AU-224 is a benzamide derivative used as a promising gastrointestinal prokinetic agent without significant side effects.
In Vivo AU-224 has excellent effect of promoting digestive motion while showing little side effect and can be orally administered[1]. AU-224 shows only weak gastrointestinal prokinetic activity after oral administration due to its low lipophilicity[2].
References

[1]. WO/2000/046201A1

[2]. Sakaguchi J, et al. An improved synthesis of butyl 4-[(4-amino-5-chloro-2-methoxybenzoyl)amino]-1-piperidineacetate (AU-224). Chem Pharm Bull (Tokyo). 2001 Jun;49(6):788-90.

Molecular Formula C19H28ClN3O4
Molecular Weight 397.9