1825355-55-2

1825355-55-2 structure

Name: Ribocil B
Chemical Name: Ribocil B
CAS Number: 1825355-55-2
Molecular Formula: C₁₉H₂₂N₆OS
Molecular Weight: 382.48
Catalog: Signaling Pathways Anti-infection Bacterial
Create Date: 2018-03-14 02:24:37
Modify Date: 2024-01-02 16:42:28
Ribocil-B is the active S-isomer of ribocil which can inhibit flavin mononucleotide (FMN) with a KD of 6.6 nM.

Name	Ribocil B

Description	Ribocil-B is the active S-isomer of ribocil which can inhibit flavin mononucleotide (FMN) with a KD of 6.6 nM.
Related Catalog	Signaling Pathways >> Anti-infection >> Bacterial Research Areas >> Infection
Target	KD: 6.6 nM (FMN)[1]
In Vitro	Ribocil-B (S-isomer) is a tight binder to the FMN riboswitch and ribocil-A (R-isomer) does not similarly interact and display antibiotic activity[1].
References	[1]. John A. Howe, et al. Atomic resolution mechanistic studies of ribocil: A highly selective unnatural ligand mimic of the E. coli FMN riboswitch.