1215333-48-4

1215333-48-4 structure

Name: GR 144053 trihydrochloride
Chemical Name: {4-[4-(4-Carbamimidoylphenyl)-1-piperazinyl]-1-piperidinyl}acetic acid trihydrochloride
CAS Number: 1215333-48-4
Molecular Formula: C₁₈H₃₀Cl₃N₅O₂
Molecular Weight: 454.82
Catalog: Signaling Pathways Cytoskeleton Integrin
Create Date: 2018-06-11 15:41:52
Modify Date: 2024-01-29 18:08:17
GR 144053 trihydrochloride is a selective and non-peptic GPIIb/IIIa inhibitor (IC50=37 nM)[1].

Name	{4-[4-(4-Carbamimidoylphenyl)-1-piperazinyl]-1-piperidinyl}acetic acid trihydrochloride
Synonyms	{4-[4-(4-Carbamimidoylphenyl)-1-piperazinyl]-1-piperidinyl}acetic acid trihydrochloride {4-[4-(4-Carbamimidoylphenyl)piperazin-1-yl]piperidin-1-yl}acetic acid trihydrochloride 1-Piperidineacetic acid, 4-[4-[4-(aminoiminomethyl)phenyl]-1-piperazinyl]-, hydrochloride (1:3)

Description	GR 144053 trihydrochloride is a selective and non-peptic GPIIb/IIIa inhibitor (IC50=37 nM)[1].
Related Catalog	Research Areas >> Cardiovascular Disease Signaling Pathways >> Cytoskeleton >> Integrin
References	[1]. Uhl B, et al. Vitronectin promotes immunothrombotic dysregulation in the venular microvasculature. Front Immunol. 2023 Feb 8;14:1078005.