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  • DC Chemicals Limited
  • China
  • Product Name: RU-505
  • Price: $Inquiry/100mg $Inquiry/250mg $Inquiry/500mg
  • Purity: 98.0%
  • Stocking Period: 3 Day
  • Contact: Tony Cao

1314206-29-5

1314206-29-5 structure
1314206-29-5 structure
  • Name: RU-505
  • Chemical Name: N-Benzyl-N-[2-(dimethylamino)ethyl]-7-(4-fluorophenyl)-2-(2-methyl-2-propanyl)pyrazolo[1,5-a]pyrimidine-5-carboxamide
  • CAS Number: 1314206-29-5
  • Molecular Formula: C28H32FN5O
  • Molecular Weight:
  • Catalog: Research Areas Neurological Disease
  • Create Date: 2018-06-16 18:10:23
  • Modify Date: 2024-01-09 21:28:38
  • RU-505 is an effective β-amyloid (Aβ)-fibrinogen interaction inhibitor with IC50s of 5.00 and 2.72 μM in fluorescence polarization (FP) and AlphaLISA assays, respectively. RU-505 is highly permeable to the BBB. RU-505 reduces cerebral amyloid angiopathy (CAA). RU-505 can be used for the research of Alzheimer’s disease (AD)[1].

Name N-Benzyl-N-[2-(dimethylamino)ethyl]-7-(4-fluorophenyl)-2-(2-methyl-2-propanyl)pyrazolo[1,5-a]pyrimidine-5-carboxamide
Synonyms N-Benzyl-N-[2-(dimethylamino)ethyl]-7-(4-fluorophenyl)-2-(2-methyl-2-propanyl)pyrazolo[1,5-a]pyrimidine-5-carboxamide
MFCD06620515
Pyrazolo[1,5-a]pyrimidine-5-carboxamide, N-[2-(dimethylamino)ethyl]-2-(1,1-dimethylethyl)-7-(4-fluorophenyl)-N-(phenylmethyl)-
RU-505
Description RU-505 is an effective β-amyloid (Aβ)-fibrinogen interaction inhibitor with IC50s of 5.00 and 2.72 μM in fluorescence polarization (FP) and AlphaLISA assays, respectively. RU-505 is highly permeable to the BBB. RU-505 reduces cerebral amyloid angiopathy (CAA). RU-505 can be used for the research of Alzheimer’s disease (AD)[1].
Related Catalog
References

[1]. Hyung Jin Ahn, et al. A novel Aβ-fibrinogen interaction inhibitor rescues altered thrombosis and cognitive decline in Alzheimer's disease mice. J Exp Med. 2014 Jun 2;211(6):1049-62.

Molecular Formula C28H32FN5O