146196-17-0

146196-17-0 structure

Name: N6-Dimethylamino methylidene-2’-deoxyisoguanosine
Chemical Name: 2'-Deoxy-N-[(dimethylamino)methylene]-2-oxo-3-hydroadenosine
CAS Number: 146196-17-0
Molecular Formula: C₁₃H₁₈N₆O₄
Molecular Weight: 322.32
Catalog: Signaling Pathways Cell Cycle/DNA Damage Nucleoside Antimetabolite/Analog
Create Date: 2018-06-30 23:58:10
Modify Date: 2024-01-31 15:20:47
N6-Dimethylamino methylidene-2’-deoxyisoguanosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

Name	2'-Deoxy-N-[(dimethylamino)methylene]-2-oxo-3-hydroadenosine
Synonyms	MFCD28976113 2'-Deoxy-N-[(dimethylamino)methylene]-2-oxo-3-hydroadenosine 3-Hydroadenosine, 2'-deoxy-N-[(dimethylamino)methylene]-2-oxo-

Description	N6-Dimethylamino methylidene-2’-deoxyisoguanosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Cell Cycle/DNA Damage >> Nucleoside Antimetabolite/Analog
References	[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.