1807521-00-1

1807521-00-1 structure

Name: Bromoacetamido-PEG4-C2-Boc
Chemical Name: 2-Methyl-2-propanyl 1-bromo-2-oxo-6,9,12,15-tetraoxa-3-azaoctadecan-18-oate
CAS Number: 1807521-00-1
Molecular Formula: C₁₇H₃₂BrNO₇
Molecular Weight: 442.342
Catalog: Signaling Pathways PROTAC PROTAC Linker
Create Date: 2018-07-08 06:51:15
Modify Date: 2024-03-07 12:58:00
Bromoacetamido-PEG4-C2-Boc is a PEG- and Alkyl/ether-based PROTAC linker can be used in the synthesis of PROTACs[1].

Name	2-Methyl-2-propanyl 1-bromo-2-oxo-6,9,12,15-tetraoxa-3-azaoctadecan-18-oate
Synonyms	MFCD28505519 2-Methyl-2-propanyl 1-bromo-2-oxo-6,9,12,15-tetraoxa-3-azaoctadecan-18-oate 6,9,12,15-Tetraoxa-3-azaoctadecan-18-oic acid, 1-bromo-2-oxo-, 1,1-dimethylethyl ester

Description	Bromoacetamido-PEG4-C2-Boc is a PEG- and Alkyl/ether-based PROTAC linker can be used in the synthesis of PROTACs[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker
Target	Alkyl/ether PEGs
In Vitro	PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References	[1]. Darren H. Wakefield, et al. Poly(vinyl ester) Polymers for In Vivo Nucleic Acid Delivery. US20130121954A1.