956707-04-3

956707-04-3 structure
956707-04-3 structure
  • Name: 8beta,9alpha-Dihydroxylindan-4(5),7(11)-dien-8alpha,12-olide
  • Chemical Name: (5aS,6aR,6bS,7S,7aR)-7,7a-Dihydroxy-3,5,6b-trimethyl-5a,6,6a,6b,7,7a-hexahydrocyclopropa[2,3]indeno[5,6-b]furan-2(4H)-one
  • CAS Number: 956707-04-3
  • Molecular Formula: C15H18O4
  • Molecular Weight: 262.301
  • Catalog: Signaling Pathways Cell Cycle/DNA Damage LIM Kinase (LIMK)
  • Create Date: 2018-07-09 14:48:18
  • Modify Date: 2024-01-31 20:03:44
  • 8β,9α-Dihydroxylindan-4(5),7(11)-dien-8alpha,12-olide (compound 3), a sesquiterpene, has anti-LIMK1 activity. 8β,9α-Dihydroxylindan-4(5),7(11)-dien-8alpha,12-olide has inhibitory property on cell motility[1].

Name (5aS,6aR,6bS,7S,7aR)-7,7a-Dihydroxy-3,5,6b-trimethyl-5a,6,6a,6b,7,7a-hexahydrocyclopropa[2,3]indeno[5,6-b]furan-2(4H)-one
Synonyms Cycloprop[2,3]indeno[5,6-b]furan-2(4H)-one, 5a,6,6a,6b,7,7a-hexahydro-7,7a-dihydroxy-3,5,6b-trimethyl-, (5aS,6aR,6bS,7S,7aR)-
(5aS,6aR,6bS,7S,7aR)-7,7a-Dihydroxy-3,5,6b-trimethyl-5a,6,6a,6b,7,7a-hexahydrocyclopropa[2,3]indeno[5,6-b]furan-2(4H)-one
Description 8β,9α-Dihydroxylindan-4(5),7(11)-dien-8alpha,12-olide (compound 3), a sesquiterpene, has anti-LIMK1 activity. 8β,9α-Dihydroxylindan-4(5),7(11)-dien-8alpha,12-olide has inhibitory property on cell motility[1].
Related Catalog
Target

LIMK1

References

[1]. Jianjiang Fu, et al. In vitro inhibitory properties of sesquiterpenes from Chloranthus serratus on cell motility via down-regulation of LIMK1 activation in human breast cancer. Phytomedicine. 2018 Oct 1;49:23-31.  

Density 1.4±0.1 g/cm3
Boiling Point 465.8±45.0 °C at 760 mmHg
Molecular Formula C15H18O4
Molecular Weight 262.301
Flash Point 178.6±22.2 °C
Exact Mass 262.120514
LogP 1.17
Vapour Pressure 0.0±2.6 mmHg at 25°C
Index of Refraction 1.634