1262897-74-4

1262897-74-4 structure
1262897-74-4 structure
  • Name: (2S)-Gemcitabine-13C,15N2 hydrochloride
  • Chemical Name: 4-Amino-1-(2-deoxy-2,2-difluoro-α-D-erythro-pentofuranosyl)-2(1H)-(2-13C,15N2)pyrimidinone hydrochloride (1:1)
  • CAS Number: 1262897-74-4
  • Molecular Formula: C813CH12ClF2N15N2O4
  • Molecular Weight: 302.639
  • Catalog: Research Areas Others
  • Create Date: 2018-06-04 06:17:38
  • Modify Date: 2024-01-10 15:21:45
  • (2S)-Gemcitabine-13C,15N2 (hydrochloride) is the 13C and 15N labeled (2S)-Gemcitabine hydrochloride[1].

Name 4-Amino-1-(2-deoxy-2,2-difluoro-α-D-erythro-pentofuranosyl)-2(1H)-(2-13C,15N2)pyrimidinone hydrochloride (1:1)
Synonyms 4-Amino-1-(2-deoxy-2,2-difluoro-α-D-erythro-pentofuranosyl)-2(1H)-(2-13C,15N2)pyrimidinone hydrochloride (1:1)
2(1H)-Pyrimidinone-2-13C-1,3-15N2, 4-amino-1-(2-deoxy-2,2-difluoro-α-D-erythro-pentofuranosyl)-, hydrochloride (1:1)
Description (2S)-Gemcitabine-13C,15N2 (hydrochloride) is the 13C and 15N labeled (2S)-Gemcitabine hydrochloride[1].
Related Catalog
In Vitro Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
References

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.  

Molecular Formula C813CH12ClF2N15N2O4
Molecular Weight 302.639
Exact Mass 302.045868