Shanghai Nianxing Industrial Co., Ltd
China
Product Name: Amino-PEG5-Boc
Price:
Purity: 95.0%
Stocking Period: 10 Day
Contact: Yang

DC Chemicals Limited
China
Product Name: Amino-PEG5-t-butyl ester
Price: $Inquiry/100mg $Inquiry/250mg $Inquiry/500mg
Purity: 98.0%
Stocking Period: 3 Day
Contact: Tony Cao

1446282-18-3

1446282-18-3 structure

1446282-18-3 structure

Name: Amino-PEG5-Boc
Chemical Name: 2-Methyl-2-propanyl 1-amino-3,6,9,12,15-pentaoxaoctadecan-18-oate
CAS Number: 1446282-18-3
Molecular Formula: C₁₇H₃₅NO₇
Molecular Weight: 365.462
Catalog: Signaling Pathways PROTAC PROTAC Linker
Create Date: 2018-06-26 10:19:49
Modify Date: 2024-01-10 21:03:21
Amino-PEG5-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name	2-Methyl-2-propanyl 1-amino-3,6,9,12,15-pentaoxaoctadecan-18-oate
Synonyms	2-Methyl-2-propanyl 1-amino-3,6,9,12,15-pentaoxaoctadecan-18-oate 3,6,9,12,15-Pentaoxaoctadecan-18-oic acid, 1-amino-, 1,1-dimethylethyl ester MFCD25424125 Amino-PEG6-t-butyl ester Amino-PEG5-t-butyl ester

Description	Amino-PEG5-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker
Target	PEGs Alkyl/ether
In Vitro	PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References	[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Density	1.0±0.1 g/cm3
Boiling Point	439.1±40.0 °C at 760 mmHg
Molecular Formula	C₁₇H₃₅NO₇
Molecular Weight	365.462
Flash Point	114.1±23.7 °C
Exact Mass	365.241364
LogP	-0.59
Vapour Pressure	0.0±1.1 mmHg at 25°C
Index of Refraction	1.457

Hazard Codes	Xn