1246820-85-8

1246820-85-8 structure

Name: Sotalol D6 hydrochloride
Chemical Name: N-(4-{1-Hydroxy-2-[(1,1,1,3,3,3-2H6)-2-propanylamino]ethyl}phenyl)methanesulfonamide hydrochloride (1:1)
CAS Number: 1246820-85-8
Molecular Formula: C₁₂H₁₅D₆ClN₂O₃S
Molecular Weight: 314.862
Catalog: Signaling Pathways GPCR/G Protein Adrenergic Receptor
Create Date: 2018-06-24 03:29:35
Modify Date: 2024-01-24 16:45:04
Sotalol D6 hydrochloride is a deuterium labeled Sotalol hydrochloride. Sotalol hydrochloride is a non-selective competitive β-adrenergic receptor antagonist that also exhibits Class III antiarrhythmic properties by its inhibition of potassium channels[1][2].

Name	N-(4-{1-Hydroxy-2-[(1,1,1,3,3,3-2H6)-2-propanylamino]ethyl}phenyl)methanesulfonamide hydrochloride (1:1)
Synonyms	Methanesulfonamide, N-[4-[1-hydroxy-2-[[1-(methyl-d3)ethyl-2,2,2-d3]amino]ethyl]phenyl]-, hydrochloride (1:1) N-(4-{1-Hydroxy-2-[(1,1,1,3,3,3-2H6)-2-propanylamino]ethyl}phenyl)methanesulfonamide hydrochloride (1:1)

Description	Sotalol D6 hydrochloride is a deuterium labeled Sotalol hydrochloride. Sotalol hydrochloride is a non-selective competitive β-adrenergic receptor antagonist that also exhibits Class III antiarrhythmic properties by its inhibition of potassium channels[1][2].
Related Catalog	Research Areas >> Cardiovascular Disease Research Areas >> Endocrinology Signaling Pathways >> GPCR/G Protein >> Adrenergic Receptor Signaling Pathways >> Membrane Transporter/Ion Channel >> Potassium Channel
Target	β-adrenergic receptor[1]; Potassium channels[1]
References	[1]. Antonaccio, M.J. and A. Gomoll, Pharmacologic basis of the antiarrhythmic and hemodynamic effects of sotalol. Am J Cardiol, 1993. 72(4): p. 27A-37A. [2]. Bertrix, L., et al., Protection against ventricular and atrial fibrillation by sotalol. Cardiovasc Res, 1986. 20(5): p. 358-63