125217-37-0

125217-37-0 structure

Name: 3’-Deoxy-3’-fluoro-5-methyluridine
Chemical Name: 3'-Deoxy-3'-fluoro-5-methyluridine
CAS Number: 125217-37-0
Molecular Formula: C₁₀H₁₃FN₂O₅
Molecular Weight: 260.22
Catalog: Signaling Pathways Cell Cycle/DNA Damage Nucleoside Antimetabolite/Analog
Create Date: 2018-06-18 23:39:06
Modify Date: 2024-01-28 08:07:07
3’-Deoxy-3’-fluoro-5-methyluridine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

Name	3'-Deoxy-3'-fluoro-5-methyluridine
Synonyms	3'-Deoxy-3'-fluoro-5-methyluridine MFCD27921028 1-(3-Deoxy-3-fluoro-β-D-ribofuranosyl)thymine Uridine, 3'-deoxy-3'-fluoro-5-methyl-

Description	3’-Deoxy-3’-fluoro-5-methyluridine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
Related Catalog	Signaling Pathways >> Cell Cycle/DNA Damage >> Nucleoside Antimetabolite/Analog Research Areas >> Others
References	[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.