1415800-44-0

1415800-44-0 structure
1415800-44-0 structure
  • Name: Bromoacetamido-PEG2-C2-acid
  • Chemical Name: 3-(2-{2-[(Bromoacetyl)amino]ethoxy}ethoxy)propanoic acid
  • CAS Number: 1415800-44-0
  • Molecular Formula: C9H16BrNO5
  • Molecular Weight: 298.131
  • Catalog: Signaling Pathways PROTAC PROTAC Linker
  • Create Date: 2018-07-13 00:00:12
  • Modify Date: 2024-01-09 12:40:38
  • Bromoacetamido-PEG2-C2-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name 3-(2-{2-[(Bromoacetyl)amino]ethoxy}ethoxy)propanoic acid
Synonyms MFCD22683317
Propanoic acid, 3-[2-[2-[(2-bromoacetyl)amino]ethoxy]ethoxy]-
3-(2-{2-[(Bromoacetyl)amino]ethoxy}ethoxy)propanoic acid
Description Bromoacetamido-PEG2-C2-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Density 1.5±0.1 g/cm3
Boiling Point 491.4±45.0 °C at 760 mmHg
Molecular Formula C9H16BrNO5
Molecular Weight 298.131
Flash Point 251.0±28.7 °C
Exact Mass 297.021179
LogP -0.59
Vapour Pressure 0.0±2.7 mmHg at 25°C
Index of Refraction 1.503