1346605-05-7

1346605-05-7 structure

Name: Propafenone-d5 (hydrochloride)
Chemical Name: 1-(2-{[2-Hydroxy-3-(propylamino)(2H5)propyl]oxy}phenyl)-3-phenyl-1-propanone hydrochloride (1:1)
CAS Number: 1346605-05-7
Molecular Formula: C₂₁H₂₃D₅ClNO₃
Molecular Weight: 382.936
Catalog: Signaling Pathways Membrane Transporter/Ion Channel Sodium Channel
Create Date: 2018-07-21 11:22:01
Modify Date: 2024-01-12 20:15:41
Propafenone D5 (SA-79 D5) hydrochloride is the deuterium labeled Propafenone hydrochloride. Propafenone (SA-79) hydrochloride is a class of anti-arrhythmic medication, which treats illnesses associated with rapid heart beats such as atrial and ventricular arrhythmias[1].

Name	1-(2-{[2-Hydroxy-3-(propylamino)(2H5)propyl]oxy}phenyl)-3-phenyl-1-propanone hydrochloride (1:1)
Synonyms	1-Propanone, 1-[2-[[2-hydroxy-3-(propylamino)propyl-1,1,2,3,3-d5]oxy]phenyl]-3-phenyl-, hydrochloride (1:1) 1-(2-{[2-Hydroxy-3-(propylamino)(2H5)propyl]oxy}phenyl)-3-phenyl-1-propanone hydrochloride (1:1)

Description	Propafenone D5 (SA-79 D5) hydrochloride is the deuterium labeled Propafenone hydrochloride. Propafenone (SA-79) hydrochloride is a class of anti-arrhythmic medication, which treats illnesses associated with rapid heart beats such as atrial and ventricular arrhythmias[1].
Related Catalog	Signaling Pathways >> Membrane Transporter/Ion Channel >> Sodium Channel Research Areas >> Cardiovascular Disease
In Vitro	Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
References	[1]. Cox L, et al. Levomepromazine for nausea and vomiting in palliative care. Cochrane Database Syst Rev. 2015;2015(11):CD009420. Published 2015 Nov 2. [2]. http://en.wikipedia.org/wiki/Propafenone