Name | N-{4-[4-(2-Methoxyphenyl)-1-piperazinyl]butyl}-4-(1,3-thiazol-4-yl)benzamide |
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Synonyms |
MFCD28118985
N-{4-[4-(2-Methoxyphenyl)-1-piperazinyl]butyl}-4-(1,3-thiazol-4-yl)benzamide Benzamide, N-[4-[4-(2-methoxyphenyl)-1-piperazinyl]butyl]-4-(4-thiazolyl)- |
Description | OS-3-106 is a potent, BBB-penetrated and selective dopamine D3 receptor (D3R) agonist. OS-3-106 binds with high affinity (Ki = 0.2 nM) at the D3R. OS-3-106 reduces cocaine self-administration and sucrose reinforcement rates. OS-3-106 can be used for psychostimulant addiction research[1]. |
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Related Catalog | |
Target |
D3 Receptor:0.2 nM (Ki) D2 Receptor |
In Vitro | OS-3-106 exhibits 115-fold binding selectivity for the D3R compared with the D2R[1]. |
References |
Density | 1.2±0.1 g/cm3 |
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Boiling Point | 671.3±55.0 °C at 760 mmHg |
Molecular Formula | C25H30N4O2S |
Molecular Weight | 450.60 |
Flash Point | 359.8±31.5 °C |
Exact Mass | 450.208954 |
LogP | 4.10 |
Vapour Pressure | 0.0±2.1 mmHg at 25°C |
Index of Refraction | 1.597 |