183906-14-1

183906-14-1 structure

Name: Biotin-β-Amyloid (1-40)
Chemical Name: 7-{[(2-Phenylethyl){[1-(tetrahydro-2-furanylmethyl)-1H-tetrazol-5-yl]methyl}amino]methyl}[1,3]dioxolo[4,5-g]quinolin-6(5H)-one
CAS Number: 183906-14-1
Molecular Formula: C₂₆H₂₈N₆O₄
Molecular Weight: 488.538
Catalog: Research Areas Neurological Disease
Create Date: 2018-06-13 07:44:11
Modify Date: 2024-01-08 11:46:13
Biotin-β-Amyloid (1-40) is a N-terminal-labelled biotinylated amyloid-ß-(1-40) peptide.

Name	7-{[(2-Phenylethyl){[1-(tetrahydro-2-furanylmethyl)-1H-tetrazol-5-yl]methyl}amino]methyl}[1,3]dioxolo[4,5-g]quinolin-6(5H)-one
Synonyms	1,3-Dioxolo[4,5-g]quinolin-6(5H)-one, 7-[[(2-phenylethyl)[[1-[(tetrahydro-2-furanyl)methyl]-1H-tetrazol-5-yl]methyl]amino]methyl]- 7-{[(2-Phenylethyl){[1-(tetrahydro-2-furanylmethyl)-1H-tetrazol-5-yl]methyl}amino]methyl}[1,3]dioxolo[4,5-g]quinolin-6(5H)-one

Description	Biotin-β-Amyloid (1-40) is a N-terminal-labelled biotinylated amyloid-ß-(1-40) peptide.
Related Catalog	Signaling Pathways >> Others >> Others Research Areas >> Neurological Disease
In Vitro	β-Amyloid (1-40) is a primary protein in plaques found in the brains of patients with Alzheimer's disease. It is the major component of senile plaque amyloids, are physiological peptides present in the brain, cerebrospinal fluid (CSF) and plasma[1]. Biotin is widely used throughout the biotechnology industry to conjugate proteins for biochemical assays. Biotin can be used for qualitative and quantitative detection, labelling or immobilisation.
References	[1]. Mikio Shoji, et al. Cerebrospinal fluid Abeta40 and Abeta42: natural course and clinical usefulness. Front Biosci. 2002 Apr 1;7:d997-1006.