19716-61-1

19716-61-1 structure

Name: 8-Oxycoptisine
Chemical Name: 6,7-Dihydro-4H-[1,3]dioxolo[4,5-g][1,3]dioxolo[7,8]isoquinolino[3,2-a]isoquinolin-4-one
CAS Number: 19716-61-1
Molecular Formula: C₁₉H₁₃NO₅
Molecular Weight: 335.310
Catalog: Research Areas Cancer
Create Date: 2018-07-11 08:30:38
Modify Date: 2024-01-11 20:18:07
8-Oxocoptisine is a natural protoberberine alkaloid with anti-cancer activity[1].

Name	6,7-Dihydro-4H-[1,3]dioxolo[4,5-g][1,3]dioxolo[7,8]isoquinolino[3,2-a]isoquinolin-4-one
Synonyms	6,7-Dihydro-4H-[1,3]dioxolo[4,5-g][1,3]dioxolo[7,8]isoquinolino[3,2-a]isoquinolin-4-one 4H-[1,3]Benzodioxolo[5,6-a]-1,3-benzodioxolo[4,5-g]quinolizin-4-one, 6,7-dihydro-

Description	8-Oxocoptisine is a natural protoberberine alkaloid with anti-cancer activity[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Others >> Others
In Vitro	8-Oxocoptisine has cytotoxicity against NCI-N87 (IC50=20.31 μM) and has no cytotoxicity against Caco-2 (IC50>100 μM)[1].
References	[1]. Ping Qian, et al. Five new alkaloids from Coptidis Rhizoma-Euodiae Fructus couple and their cytotoxic activities against gastrointestinal cancer cells. Fitoterapia. 2014 Mar;93:74-80.