1055035-48-7

1055035-48-7 structure

Name: 2-Amino-6-chloro-9-(3-deoxy-beta-D-ribofuanosyl)-9H-purine
Chemical Name: 6-Chloro-9-(3-deoxy-β-D-erythro-pentofuranosyl)-9H-purin-2-amine
CAS Number: 1055035-48-7
Molecular Formula: C₁₀H₁₂ClN₅O₃
Molecular Weight: 285.69
Catalog: Signaling Pathways Cell Cycle/DNA Damage Nucleoside Antimetabolite/Analog
Create Date: 2018-06-28 09:33:25
Modify Date: 2023-06-01 10:22:06
2-Amino-6-chloro-9-(3-deoxy-beta-D-ribofuanosyl)-9H-purine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

Name	6-Chloro-9-(3-deoxy-β-D-erythro-pentofuranosyl)-9H-purin-2-amine
Synonyms	6-Chloro-9-(3-deoxy-β-D-erythro-pentofuranosyl)-9H-purin-2-amine 9H-Purin-2-amine, 6-chloro-9-(3-deoxy-β-D-erythro-pentofuranosyl)-

Description	2-Amino-6-chloro-9-(3-deoxy-beta-D-ribofuanosyl)-9H-purine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Cell Cycle/DNA Damage >> Nucleoside Antimetabolite/Analog
References	[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.