114652-80-1

114652-80-1 structure

Name: 2'-Deoxy-2'-fluoro-5-trifluoromethyl-arabinouridine
Chemical Name: 1-(2-Deoxy-2-fluoro-β-D-arabinofuranosyl)-5-(trifluoromethyl)-2,4(1H,3H)-pyrimidinedione
CAS Number: 114652-80-1
Molecular Formula: C₁₀H₁₀F₄N₂O₅
Molecular Weight: 314.19
Catalog: Signaling Pathways Cell Cycle/DNA Damage Nucleoside Antimetabolite/Analog
Create Date: 2018-06-27 23:44:09
Modify Date: 2024-01-08 18:53:18
2′-Deoxy-2′-fluoro-5-triflu oromethyl-arabinouridine is a thymidine analogue. Analogs of this series have insertional activity towards replicated DNA. They can be used to label cells and track DNA synthesis[1].

Name	1-(2-Deoxy-2-fluoro-β-D-arabinofuranosyl)-5-(trifluoromethyl)-2,4(1H,3H)-pyrimidinedione
Synonyms	1-(2-Deoxy-2-fluoro-β-D-arabinofuranosyl)-5-(trifluoromethyl)-2,4(1H,3H)-pyrimidinedione 2,4(1H,3H)-Pyrimidinedione, 1-(2-deoxy-2-fluoro-β-D-arabinofuranosyl)-5-(trifluoromethyl)- MFCD00877795

Description	2′-Deoxy-2′-fluoro-5-triflu oromethyl-arabinouridine is a thymidine analogue. Analogs of this series have insertional activity towards replicated DNA. They can be used to label cells and track DNA synthesis[1].
Related Catalog	Signaling Pathways >> Cell Cycle/DNA Damage >> Nucleoside Antimetabolite/Analog Research Areas >> Others
References	[1]. Cavanagh BL, et al. Thymidine analogues for tracking DNA synthesis. Molecules. 2011 Sep 15;16(9):7980-93.