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1394238-91-5

1394238-91-5 structure
1394238-91-5 structure
  • Name: Fmoc-Val-Ala-PAB-OH
  • Chemical Name: N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-L-valyl-N-[4-(hydroxymethyl)phenyl]-L-alaninamide
  • CAS Number: 1394238-91-5
  • Molecular Formula: C30H33N3O5
  • Molecular Weight: 515.600
  • Catalog: Signaling Pathways Antibody-drug Conjugate ADC Linker
  • Create Date: 2018-06-04 08:13:23
  • Modify Date: 2024-01-13 15:04:49
  • Fmoc-Val-Ala-PAB-OH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

Name N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-L-valyl-N-[4-(hydroxymethyl)phenyl]-L-alaninamide
Synonyms MFCD29078523
N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-L-valyl-N-[4-(hydroxymethyl)phenyl]-L-alaninamide
L-Alaninamide, N-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-valyl-N-[4-(hydroxymethyl)phenyl]-
Description Fmoc-Val-Ala-PAB-OH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].
Related Catalog
Target

Cleavable

In Vitro ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker[1].
References

[1]. Beck A, et al. Strategies and challenges for the next generation of antibody-drug conjugates. Nat Rev Drug Discov. 2017 May;16(5):315-337.

Density 1.3±0.1 g/cm3
Boiling Point 811.1±65.0 °C at 760 mmHg
Melting Point 218 °C(dec.)
Molecular Formula C30H33N3O5
Molecular Weight 515.600
Flash Point 444.4±34.3 °C
Exact Mass 515.242004
LogP 4.13
Vapour Pressure 0.0±3.0 mmHg at 25°C
Index of Refraction 1.620
Hazard Codes Xi