688036-19-3
688036-19-3 structure
- Name: SU-11752
- Chemical Name: 3-(2,4-Diethyl-5-{(Z)-[2-oxo-5-(phenylsulfamoyl)-1,2-dihydro-3H-indol-3-ylidene]methyl}-1H-pyrrol-3-yl)propanoic acid
- CAS Number: 688036-19-3
- Molecular Formula: C26H27N3O5S
- Molecular Weight: 493.575
- Create Date: 2018-06-06 23:30:52
- Modify Date: 2024-03-02 07:03:59
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SU-11752 is a potent, selective inhibitor of DNA-PK, >500-fold selectivity over PI3Kγ, inhibits DNA double-strand break repair in cells and sensitizs ionizing radiation in cancer cells..
| Name | 3-(2,4-Diethyl-5-{(Z)-[2-oxo-5-(phenylsulfamoyl)-1,2-dihydro-3H-indol-3-ylidene]methyl}-1H-pyrrol-3-yl)propanoic acid |
|---|---|
| Synonyms |
1H-Pyrrole-3-propanoic acid, 5-[(Z)-[1,2-dihydro-2-oxo-5-[(phenylamino)sulfonyl]-3H-indol-3-ylidene]methyl]-2,4-diethyl-
3-(2,4-Diethyl-5-{(Z)-[2-oxo-5-(phenylsulfamoyl)-1,2-dihydro-3H-indol-3-ylidene]methyl}-1H-pyrrol-3-yl)propanoic acid |
| Density | 1.4±0.1 g/cm3 |
|---|---|
| Molecular Formula | C26H27N3O5S |
| Molecular Weight | 493.575 |
| Exact Mass | 493.167145 |
| LogP | 4.61 |
| Index of Refraction | 1.663 |