Shanghai Nianxing Industrial Co., Ltd
China
Product Name: SU 5614
Price:
Purity: 98.0%
Stocking Period: 10 Day
Contact: Yang

DC Chemicals Limited
China
Product Name: SU5614
Price: $300.0/100mg $600.0/250mg $1200.0/1g
Purity: 98.0%
Stocking Period: 3 Day
Contact: Tony Cao

ShangHai DC Chemicals Co.,Ltd
China
Product Name: SU5614
Price: ￥Inquiry/1g
Purity: 98.9%
Stocking Period: 1 Day
Contact: Tony Lai

Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: 5-CHLORO-3-[(3,5-DIMETHYLPYRROL-2-YL)METHYLENE]-2-INDOLINONE
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Stocking Period: Inquiry
Contact: Ms Wang

1055412-47-9

1055412-47-9 structure

1055412-47-9 structure

Name: SU 5614
Chemical Name: 5-Chloro-3-[(3,5-dimethyl-1H-pyrrol-2-yl)methylene]-1,3-dihydro-2 H-indol-2-one
CAS Number: 1055412-47-9
Molecular Formula: C₁₅H₁₃ClN₂O
Molecular Weight: 272.73000
Create Date: 2017-03-17 18:31:28
Modify Date: 2024-01-10 10:24:08
(Z)-SU5614 is a potent FLT3 inhibitor and selectively induces growth arrest, apoptosis, and cell cycle arrest in Ba/F3 and AML cell lines expressing a constitutively activated FLT3[1].

Name	5-Chloro-3-[(3,5-dimethyl-1H-pyrrol-2-yl)methylene]-1,3-dihydro-2 H-indol-2-one
Synonyms	5-Chloro-3-[(3,5-dimethylpyrrol-2-yl)methylene]-2-indolinone 1H-Indole-2-carboxylic acid,5-chloro-3-[(3,5-dimethylphenyl)sulfonyl] 5-chloro-3-(3,5-dimethylphenyl-sulfonyl)indole-2-carboxylic acid 5-chloro-3-(3,5-dimethyl-1H-pyrrol-2-yl-methylene)-1,3-dihydro-indol-2-one 5-chloro-3-[(3,5-dimethylphenyl)sulfonyl]-1H-indole-2-carboxylic acid 3-[(3,5-dimethylphenyl)sulfonyl]-1H-indole-2-carboxylic acid SU 5614 SU5614

Description	(Z)-SU5614 is a potent FLT3 inhibitor and selectively induces growth arrest, apoptosis, and cell cycle arrest in Ba/F3 and AML cell lines expressing a constitutively activated FLT3[1].
Related Catalog	Signaling Pathways >> Apoptosis >> Apoptosis Research Areas >> Cancer Signaling Pathways >> Protein Tyrosine Kinase/RTK >> FLT3
References	[1]. Spiekermann K, et al. The protein tyrosine kinase inhibitor SU5614 inhibits FLT3 and induces growth arrest and apoptosis in AML-derived cell lines expressing a constitutively activated FLT3. Blood. 2003 Feb 15;101(4):1494-504.

Molecular Formula	C₁₅H₁₃ClN₂O
Molecular Weight	272.73000
Exact Mass	272.07200
PSA	48.38000
LogP	3.86270

Hazard Statements	H413
RIDADR	NONH for all modes of transport
HS Code	2933990090

HS Code	2933990090
Summary	2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%