937205-20-4

937205-20-4 structure

Name: N-[2-[4-(1-Methylethyl)phenoxy]acetyl]guanosine
Chemical Name: N-[(4-Isopropylphenoxy)acetyl]guanosine
CAS Number: 937205-20-4
Molecular Formula: C₂₁H₂₅N₅O₇
Molecular Weight: 459.45
Catalog: Signaling Pathways Cell Cycle/DNA Damage Nucleoside Antimetabolite/Analog
Create Date: 2018-07-16 02:53:30
Modify Date: 2024-01-31 06:08:13
N-[2-[4-(1-Methylethyl)phenoxy]acetyl]guanosine is a guanosine analog. Some guanosine analogs have immunostimulatory activity. In some animal models, they also induce type I interferons, producing antiviral effects. Studies have shown that the functional activity of guanosine analogs is dependent on the activation of Toll-like receptor 7 (TLR7)[1].

Name	N-[(4-Isopropylphenoxy)acetyl]guanosine
Synonyms	N-[(4-Isopropylphenoxy)acetyl]guanosine Guanosine, N-[2-[4-(1-methylethyl)phenoxy]acetyl]-

Description	N-[2-[4-(1-Methylethyl)phenoxy]acetyl]guanosine is a guanosine analog. Some guanosine analogs have immunostimulatory activity. In some animal models, they also induce type I interferons, producing antiviral effects. Studies have shown that the functional activity of guanosine analogs is dependent on the activation of Toll-like receptor 7 (TLR7)[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Cell Cycle/DNA Damage >> Nucleoside Antimetabolite/Analog
References	[1]. Lee J, et al. Molecular basis for the immunostimulatory activity of guanine nucleoside analogs: activation of Toll-like receptor 7. Proc Natl Acad Sci U S A. 2003 May 27;100(11):6646-51.