129885-95-6

129885-95-6 structure
129885-95-6 structure
  • Name: 1-(3-Deoxy-3-fluoro-β-D-xylofuranosyl)-2,4(1H,3H)-pyrimidinedione
  • Chemical Name: 1-(3-Deoxy-3-fluoro-β-D-xylofuranosyl)-2,4(1H,3H)-pyrimidinedione
  • CAS Number: 129885-95-6
  • Molecular Formula: C9H11FN2O5
  • Molecular Weight: 246.19
  • Catalog: Signaling Pathways Cell Cycle/DNA Damage Nucleoside Antimetabolite/Analog
  • Create Date: 2018-07-08 13:42:56
  • Modify Date: 2024-09-24 01:25:00
  • 1-(3-Deoxy-3-fluoro-β-D-xylofuranosyl)-2,4(1H,3H)-pyrimidinedione is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

Name 1-(3-Deoxy-3-fluoro-β-D-xylofuranosyl)-2,4(1H,3H)-pyrimidinedione
Synonyms 1-(3-Deoxy-3-fluoro-β-D-xylofuranosyl)-2,4(1H,3H)-pyrimidinedione
2,4(1H,3H)-Pyrimidinedione, 1-(3-deoxy-3-fluoro-β-D-xylofuranosyl)-
1-(3-Deoxy-3-fluoro-β-D-xylofuranosyl)pyrimidine-2,4(1H,3H)-dione
Description 1-(3-Deoxy-3-fluoro-β-D-xylofuranosyl)-2,4(1H,3H)-pyrimidinedione is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
Related Catalog
References

[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.  

Density 1.6±0.1 g/cm3
Molecular Formula C9H11FN2O5
Molecular Weight 246.19
Exact Mass 246.065201
LogP -1.18
Index of Refraction 1.608