1793055-06-7

1793055-06-7 structure

Name: Pirimiphos-methyl-d6
Chemical Name: O-[2-(Diethylamino)-6-methyl-4-pyrimidinyl] O,O-bis[(2H3)methyl] phosphorothioate
CAS Number: 1793055-06-7
Molecular Formula: C₁₁H₁₄D₆N₃O₃PS
Molecular Weight: 311.371
Catalog: Signaling Pathways Neuronal Signaling AChE
Create Date: 2018-07-13 05:26:46
Modify Date: 2024-01-02 12:18:00
Pirimiphos-methyl-d6 is the deuterium labeled Pirimiphos-methyl. Pirimiphos-methyl is a rapid-acting organophosphorus insecticide and acaricide, causing inhibition of AChE in target organisms. Pirimiphos-methyl is often used for prevention and control of beetles, snout beetles, moths and Ephestia cautella during storage of agricultural grains[1][2][3].

Name	O-[2-(Diethylamino)-6-methyl-4-pyrimidinyl] O,O-bis[(2H3)methyl] phosphorothioate
Synonyms	Phosphorothioic acid, O-[2-(diethylamino)-6-methyl-4-pyrimidinyl] O,O-dimethyl-d3 ester O-[2-(Diethylamino)-6-methyl-4-pyrimidinyl] O,O-bis[(2H3)methyl] phosphorothioate

Description	Pirimiphos-methyl-d6 is the deuterium labeled Pirimiphos-methyl. Pirimiphos-methyl is a rapid-acting organophosphorus insecticide and acaricide, causing inhibition of AChE in target organisms. Pirimiphos-methyl is often used for prevention and control of beetles, snout beetles, moths and Ephestia cautella during storage of agricultural grains[1][2][3].
Related Catalog	Research Areas >> Infection Signaling Pathways >> Neuronal Signaling >> AChE
In Vitro	Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
References	[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [2]. Shizhuang Weng, et al. Detection of Pirimiphos-Methyl in Wheat Using Surface-Enhanced Raman Spectroscopy and Chemometric Methods. Molecules. 2019 Apr 30;24(9):1691. [3]. Pål A Olsvik, et al. In Vitro Toxicity of Pirimiphos-Methyl in Atlantic Salmon Hepatocytes. Toxicol In Vitro. 2017 Mar;39:1-14. [4]. Esther Borrás, et al. Atmospheric Degradation of the Organothiophosphate Insecticide - Pirimiphos-methyl. Sci Total Environ. 2017 Feb 1;579:1-9.