Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: H-PRO-ALA-LEU-PRO-GLU-ASP-GLY-GLY-SER-GLY-ALA-PHE-PRO-PRO-GLY-HIS-PHE-LYS-ASP-PRO-LYS-ARG-LEU-TYR-OH
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Purity: 98.0%
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211362-85-5

211362-85-5 structure

Name: H-PRO-ALA-LEU-PRO-GLU-ASP-GLY-GLY-SER-GLY-ALA-PHE-PRO-PRO-GLY-HIS-PHE-LYS-ASP-PRO-LYS-ARG-LEU-TYR-OH
Chemical Name: L-Prolyl-L-alanyl-L-leucyl-L-prolyl-L-α-glutamyl-L-α-aspartylglycylglycyl-L-serylglycyl-L-alanyl-L-phenylalanyl-L-prolyl-L-prolylglycyl-L-histidyl-L-phenylalanyl-L-lysyl-L-α-aspartyl-L-prolyl-L-lysyl-L-arginyl-L-leucyl-L-tyrosine
CAS Number: 211362-85-5
Molecular Formula: C₁₁₈H₁₇₃N₃₁O₃₃
Molecular Weight: 2553.824
Catalog: Signaling Pathways Anti-infection Bacterial
Create Date: 2018-07-15 11:47:06
Modify Date: 2024-01-02 06:08:40
Brain Derived Basic Fibroblast Growth Factor (1-24) (FGF basic 1-24) is a synthetic peptide, shows anti-bacterial and anti-HBV activities. Brain Derived Basic Fibroblast Growth Factor (1-24) can be used in infection disease and immune disease research[1].

Name	L-Prolyl-L-alanyl-L-leucyl-L-prolyl-L-α-glutamyl-L-α-aspartylglycylglycyl-L-serylglycyl-L-alanyl-L-phenylalanyl-L-prolyl-L-prolylglycyl-L-histidyl-L-phenylalanyl-L-lysyl-L-α-aspartyl-L-prolyl-L-lysyl-L-arginyl-L-leucyl-L-tyrosine
Synonyms	L-Prolyl-L-alanyl-L-leucyl-L-prolyl-L-α-glutamyl-L-α-aspartylglycylglycyl-L-serylglycyl-L-alanyl-L-phenylalanyl-L-prolyl-L-prolylglycyl-L-histidyl-L-phenylalanyl-L-lysyl-L-α-aspartyl-L-pro lyl-L-lysyl-L-arginyl-L-leucyl-L-tyrosine L-Tyrosine, L-prolyl-L-alanyl-L-leucyl-L-prolyl-L-α-glutamyl-L-α-aspartylglycylglycyl-L-serylglycyl-L-alanyl-L-phenylalanyl-L-prolyl-L-prolylglycyl-L-histidyl-L-phenylalanyl-L-lysyl-L-α-as partyl-L-prolyl-L-lysyl-L-arginyl-L-leucyl-

Description	Brain Derived Basic Fibroblast Growth Factor (1-24) (FGF basic 1-24) is a synthetic peptide, shows anti-bacterial and anti-HBV activities. Brain Derived Basic Fibroblast Growth Factor (1-24) can be used in infection disease and immune disease research[1].
Related Catalog	Research Areas >> Infection Signaling Pathways >> Anti-infection >> HBV Research Areas >> Inflammation/Immunology Signaling Pathways >> Anti-infection >> Bacterial
In Vitro	Brain Derived Basic Fibroblast Growth Factor (1-24) (10 μg/mL; 12 h) inhibits the growth of Streptococcus pneumoniae[1]. Brain Derived Basic Fibroblast Growth Factor (1-24) (10 μg/mL; 6 d) inhibits HBV replication of HepG2-2.2.15 cells[1]. Brain Derived Basic Fibroblast Growth Factor (1-24) (10 μg/mL; 22 h) inhibits the migration of human endothelial cell[1]. Cell Viability Assay[1] Cell Line: Streptococcus pneumoniae Concentration: 10 μg/mL Incubation Time: 12 hours Result: Inhibited by 100% the growth of Streptococcus pneumoniae. RT-PCR[1] Cell Line: HepG2-2.2.15 cells Concentration: 10 μg/mL Incubation Time: 6 days Result: Inhibited by 31.4% HBV replication as compared to the virus control infection. Cell Migration Assay [1] Cell Line: Human endothelial cells (HUVEC) Concentration: 10 μg/mL Incubation Time: 22 hours Result: Inhibited by 17% the migration of human endothelial cells
References	[1]. Dorian Bevec, et al. Use of bfgf 1-24 and optionally (arg 8) vasopressin to treat eg s. pneumoniae infection. WO2009039980A2.