682329-63-1

682329-63-1 structure

Name: Cytostatin
Chemical Name: (2S,5S,6S,7S,8Z,10Z,12E)-7-Hydroxy-6-methyl-2-[(2S,3S)-3-methyl-6-oxo-3,6-dihydro-2H-pyran-2-yl]-8,10,12-tetradecatrien-5-yl dihydrogen phosphate
CAS Number: 682329-63-1
Molecular Formula: C₂₁H₃₃O₇P
Molecular Weight: 428.456
Catalog: Signaling Pathways Metabolic Enzyme/Protease Phosphatase
Create Date: 2018-06-17 03:11:13
Modify Date: 2024-01-14 12:55:20
Cytostatin is a potent and selective inhibitor of PP2A with promising antitumor activity. Cytostatin belongs to the fostriecin family of natural products[1].

Name	(2S,5S,6S,7S,8Z,10Z,12E)-7-Hydroxy-6-methyl-2-[(2S,3S)-3-methyl-6-oxo-3,6-dihydro-2H-pyran-2-yl]-8,10,12-tetradecatrien-5-yl dihydrogen phosphate
Synonyms	(2S,5S,6S,7S,8Z,10Z,12E)-7-Hydroxy-6-methyl-2-[(2S,3S)-3-methyl-6-oxo-3,6-dihydro-2H-pyran-2-yl]-8,10,12-tetradecatrien-5-yl dihydrogen phosphate 2H-Pyran-2-one, 5,6-dihydro-6-[(1S,4S,5S,6S,7Z,9Z,11E)-6-hydroxy-1,5-dimethyl-4-(phosphonooxy)-7,9,11-tridecatrien-1-yl]-5-methyl-, (5S,6S)-

Description	Cytostatin is a potent and selective inhibitor of PP2A with promising antitumor activity. Cytostatin belongs to the fostriecin family of natural products[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Metabolic Enzyme/Protease >> Phosphatase
Target	PP2A[1]
References	[1]. Lawhorn BG, et al. Total synthesis and evaluation of cytostatin, its C10-C11 diastereomers, and additional key analogues: impact on PP2A inhibition. J Am Chem Soc. 2006;128(51):16720-16732.

Hazard Codes	Xi