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  • BioBioPha
  • China
  • Product Name: Coclaurine
  • Price: ¥800.0/5mg
  • Purity: 98.0%
  • Stocking Period: 10 Day
  • Contact: Xueping-Zheng


486-39-5

486-39-5 structure
486-39-5 structure
  • Name: Coclaurine
  • Chemical Name: (RS)-coclaurine
  • CAS Number: 486-39-5
  • Molecular Formula: C17H19NO3
  • Molecular Weight: 285.338
  • Catalog: Natural product Alkaloid
  • Create Date: 2016-01-12 00:33:40
  • Modify Date: 2024-01-08 07:37:35
  • Coclaurine is a class of tetrahydroisoquinoline alkaloids isolated from Sarcopetalum harveyanum. Coclaurine is a nicotinic acetylcholine receptor (nAChRs) antagonist[1][2].

Name (RS)-coclaurine
Synonyms (1S)-1-(4-Hydroxybenzyl)-6-methoxy-1,2,3,4-tetrahydro-7-isoquinolinol
Coclaurine
1-(4-Hydroxybenzyl)-6-methoxy-1,2,3,4-tetrahydroisoquinolin-7-ol
Isoquinolin-7-ol, 1-[4-hydroxybenzyl]-1,2,3,4-tetrahydro-6-methoxy-
1-(4-Hydroxybenzyl)-6-methoxy-1,2,3,4-tetrahydro-7-isoquinolinol
7-Isoquinolinol, 1,2,3,4-tetrahydro-1-[(4-hydroxyphenyl)methyl]-6-methoxy-, (1S)-
Machiline
1-(p-Hydroxybenzyl)-6-methoxy-7-hydroxy-1,2,3,4-tetrahydroisoquinoline
1,2,3,4-Tetrahydro-1-(p-hydroxybenzyl)-6-methoxy-7-isoquinolinol
7-Isoquinolinol, 1,2,3,4-tetrahydro-1-[(4-hydroxyphenyl)methyl]-6-methoxy-
6-Methoxy-7-hydroxy-(1R)-[(4-hydroxyphenyl)methyl]-1,2,3,4-tetrahydroisoquinoline
Description Coclaurine is a class of tetrahydroisoquinoline alkaloids isolated from Sarcopetalum harveyanum. Coclaurine is a nicotinic acetylcholine receptor (nAChRs) antagonist[1][2].
Related Catalog
References

[1]. Sowemimo BO, et al. The isolation of stepharine and coclaurine from Sarcopetalum harveyanum. Lloydia. 1972 Mar;35(1):90-1.

[2]. Matthew J. Cheesman . Oceania: Antidepressant Medicinal Plants. Herbal Medicine in Depression. 2016, 483-527.

Density 1.2±0.1 g/cm3
Boiling Point 496.9±45.0 °C at 760 mmHg
Melting Point 220-221°
Molecular Formula C17H19NO3
Molecular Weight 285.338
Flash Point 254.3±28.7 °C
Exact Mass 285.136505
PSA 61.72000
LogP 1.72
Vapour Pressure 0.0±1.3 mmHg at 25°C
Index of Refraction 1.621
Hazard Codes Xi
Precursor  0

DownStream  1