1217601-58-5
1217601-58-5 structure
- Name: (S)-Pramipexole-d5 (hydrochloride)
- Chemical Name: (S)-PraMipexole-d5 Dihydrochloride
- CAS Number: 1217601-58-5
- Molecular Formula:
- Molecular Weight:
- Catalog: Signaling Pathways GPCR/G Protein Dopamine Receptor
- Create Date: 2018-06-12 16:43:37
- Modify Date: 2024-01-09 17:06:44
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Pramipexole-d5 (dihydrochloride) is deuterium labeled Pramipexole (dihydrochloride). Pramipexole dihydrochloride is a selective and blood-brain barrier (BBB) penetrant dopamine D2-type receptor agonist, with Kis of 2.2 nM, 3.9 nM, 0.5 nM and 1.3 nM for D2-type receptor, D2, D3 and D4 receptors, respectively. Pramipexole dihydrochloride can be used for the research of Parkinson's disease (PD) and restless legs syndrome (RLS)[1][2][3].
| Name | (S)-PraMipexole-d5 Dihydrochloride |
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| Description | Pramipexole-d5 (dihydrochloride) is deuterium labeled Pramipexole (dihydrochloride). Pramipexole dihydrochloride is a selective and blood-brain barrier (BBB) penetrant dopamine D2-type receptor agonist, with Kis of 2.2 nM, 3.9 nM, 0.5 nM and 1.3 nM for D2-type receptor, D2, D3 and D4 receptors, respectively. Pramipexole dihydrochloride can be used for the research of Parkinson's disease (PD) and restless legs syndrome (RLS)[1][2][3]. |
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| Related Catalog | |
| In Vitro | Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1]. |
| References |
| No Any Chemical & Physical Properties |