1359944-60-7
1359944-60-7 structure
- Name: MRT-83 hydrochloride
- Chemical Name: MRT-83 hydrochloride
- CAS Number: 1359944-60-7
- Molecular Formula:
- Molecular Weight:
- Catalog: Signaling Pathways Stem Cell/Wnt Smo
- Create Date: 2018-07-03 18:06:33
- Modify Date: 2024-01-09 19:10:19
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MRT-83 (hydrochloride) is the potent antagonist of Smoothened (Smo) receptor. MRT-83 (hydrochloride) inhibits the Hedgehog (Hh) signaling pathway and BODIPY-cyclopamine binding to human Smo. MRT-83 (hydrochloride) has the potential for researching cancer disease[1].
| Name | MRT-83 hydrochloride |
|---|
| Description | MRT-83 (hydrochloride) is the potent antagonist of Smoothened (Smo) receptor. MRT-83 (hydrochloride) inhibits the Hedgehog (Hh) signaling pathway and BODIPY-cyclopamine binding to human Smo. MRT-83 (hydrochloride) has the potential for researching cancer disease[1]. |
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| Related Catalog | |
| Target |
Smo[1] |
| In Vitro | MRT-83 (hydrochloride) (compound 86) has IC50s of 15 and 11 nM respectively in Shh-light2 and C3H10T1/2 cells in the biological activity assay[1]. |
| References |
| No Any Chemical & Physical Properties |