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1415800-37-1

1415800-37-1 structure
1415800-37-1 structure
  • Name: Bromoacetamido-PEG5-azide
  • Chemical Name: Bromoacetamido-PEG5 -Azide
  • CAS Number: 1415800-37-1
  • Molecular Formula: C14H27BrN4O6
  • Molecular Weight: 427.29
  • Catalog: Signaling Pathways PROTAC PROTAC Linker
  • Create Date: 2018-06-15 07:22:29
  • Modify Date: 2024-01-08 20:05:06
  • Bromoacetamido-PEG5-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name Bromoacetamido-PEG5 -Azide
Description Bromoacetamido-PEG5-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Molecular Formula C14H27BrN4O6
Molecular Weight 427.29